ceesdekker.net Fundamentals Explained

ceesdekker.net Fundamentals Explained

Blog Article

Rotary movement of DNA rotors on nanopores. Best row: Uncooked video clip of the Cy5 channel of every rotor. Middle row: corresponding one-particle localization benefits of each finishes from the DNA rotors. The posture of the current body is marked as orange and blue dots, as well as the trajectory of The ten frames just before The existing frame is revealed as sound strains.

1996, very first mesoscopic demand density waves devices; and initially electrical measurements on a single metal nanocluster involving nanoelectrodes

Multicolor imaging on the bacterial nucleoid and cell division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins

Since 2000, Dekker has shifted the leading focus of his perform to biophysics where he scientific studies the Houses of one biomolecules and cells using the equipment of nanotechnology. This modification of field was driven by his fascination to the extraordinary functioning of biological molecular structures, and also because of the extensive-term viewpoint that lots of exciting discoveries is often envisioned in this area.[5] Existing traces of investigation in his biophysics team are from the parts of:[six]

2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and first at any time research of your dynamics DNA supercoils and the discovery of supercoil hopping

Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers cees dekker and fluorescence,

You are a Christian. If you could make this type of synthetic mobile, would you be a single move closer to God, or would the role of God have diminished rather once more?

Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative manner

This "Cited by" count involves citations to the next article content in Scholar. Those marked * may be distinct through the short article during the profile.

There was a single dilemma while — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers were being actually not this sort of wonderful conductors, which was relatively disappointing. We Consequently broadened our watch to test to search out extra promising molecules.

An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes

Numerous new phenomena were being identified, and he and his research team established a number one place During this discipline of research. Dekker and his exploration group learned new physics of nanotubes along with explored the feasibility of molecular electronics. In 1998, they were being the initial to make a transistor based upon just one nanotube molecule.

As an example, we look at the nucleopore elaborate, a gateway concerning the cell nucleus and the cytoplasm. This is a really challenging program and therefore tricky to examine inside a mobile, so we use biomimetics. We reconstruct holes then insert person features on the nucleopore complicated to check transport through it at The only-molecule level.’

It absolutely was a really appealing time, during which I acquired many support from Delft University of Technological innovation, where by I was a professor at time, and I started off a number of collaborations with molecular biologists. That assisted me study lots.’